Industry Intelligence

The State of Diabetes Device Technology and Intellectual Property


Posted in Intellectual Property by Camilla Andersson on October 30, 2012

To serve a surging patient population, companies will need a robust product and intellectual property portfolio to maximise growth.


Diabetes mellitus has become a growing global worldwide healthcare concern. It is the fifth leading cause of death in the majority of developed countries and is becoming an increasingly larger issue in emerging economies. The International Diabetes Federation (IDF) estimates the prevalence of diabetes to be 366 million people worldwide in 2011, and projects the disease to affect 550 million people and cost over US$500 billion annually by 2030. UBM TechInsights, in conjunction with Espicom, a noted medical market research firm, recently completed an analysis that included not just a market overview, but also a deep dive into the technology and intellectual property (IP) associated with the state of medical device treatment for this growing epidemic.

The analysis focused specifically on medical devices, with exclusions for drugs, transplants/cell replacement and generic chronic illness monitoring systems. Even so, the expenditure on device technologies and related systems needed to address the diabetes pandemic will reach US$18 billion in less than five years. Key findings include:

  • Noninvasive monitoring and delivery technologies have yet to deliver consistent performance, as vendors continue to develop various approaches to a solution.
  • Discerning companies are leveraging intellectual property in the development of systems and algorithms to deliver more consistent performance to both caregivers and patients. Growth in software and algorithm development has been impressive: the number of grants and applications has doubled during the last six years.
  • Although a few large companies have a substantial share of the current diabetes device market, they continue to have large gaps in their patent and product portfolios, providing opportunities for potential disruption.
  • As an increasing number of diabetes patients and caregivers turn to more portable and consumer-friendly devices, companies will need a strong product and IP portfolio to maximise growth. This confluence of consumer and medical technology will prove to be a particular challenge to the medical industry because of the inherent cultural differences in the development of consumer and medical devices.
  • The possible development of an artificial pancreas using medical device technology remains just that—a possibility—because of technical, biological and regulatory issues.

The remainder of this article will focus on the technology and IP analysis results, providing a glimpse into past and future technology areas. To supplement the information presented around the IP analysis, TechInsights has an active teardown programme that has evaluated and analysed a number of the popular blood glucose monitors (BGMs), continuous glucose monitors (CGMs) and insulin pumps. Examples of the internals of some of those products will be presented as well as additional perspectives.

 

Figure 1: Diabetes patents timeline.

 

 

Establishing correlations

A framework was devised to partition the problem into manageable segments that would facilitate an analysis of the products and technologies associated with diabetes. This approach resulted in 17 categories ranging from simple blood tests to an artificial pancreas. The IP, more specifically the patents, associated with each of these partitions was then collected, assessed and evaluated for relevance to the category. Finally, the technical and IP analyses were correlated against the marketing assessment, permitting a top-to-bottom connection between the companies, products, technology and medical device IP associated with the monitoring and treatment of diabetes.

A fairly generic search of diabetes-related patents in which the keyword diabetes was found in the patent claims generated more than 100,500 patents with patent activity beginning as early as 1969. The top 10 categories by International Patent Classification (IPC) code are all essentially drug-related patents and account for more than 51,000 of them. A screening process, including limiting the data set to medical device patents, resulted in almost 5900 unique patents (the data set) that were placed into the technology subcategories for individual review and analysis. Before diving into the details of one of these categories, a look at some of the characteristics of the overall data set is in order.

      

Figure 2: BGM and test strip top assignees (Green—further analysis in report). 

 The timing and distribution of the priority dates for the 100,000-plus patents associated with diabetes are detailed in Figure 1. The late 1990s saw a dramatic increase in the number of patents, with a peak occurring in 2005. This rapid increase followed a long period of stasis and very slow technology adoption from the development of long-acting insulin in the 1940s to the 1980s. The advent of small BGMs in the 1980s accelerated testing by the individual patient, providing a more efficient method of monitoring and treating this chronic illness. These events also prompted the development of specialists who could focus on treatment of the disease. The first insulin pumps were created in 1979. They were large and had to be carried in a backpack and, consequently, were quite inconvenient. Finally, the Diabetes Control and Complications Trial (DCCT) was conducted from 1983 to 1993, demonstrating that people who could manage their glucose level were less likely to contract long-term complications. Thus, a number of developments converging in the 1980s and 1990s spurred new thinking in the treatment of diabetes and triggered greater innovation across the technology groups. The peak in 2005 and 2006 reflects the large increase in innovation that had occurred during this timeframe with new products built on preceding technology. However, the drop in the number of patents since that time probably corresponds to several factors, including:

  • maturing of the technology that led to more incremental innovations in established areas;
  • a new plateau of tech and treatment options with new approaches becoming more efficient, profitable and sustainable in the long run for an ever larger percentage of patients;
  • general uncertainty around reimbursement issues.
 Figure 3: BGM and test strip—priority date by top assignees.

Emerging markets drive demand for SMBG
To illustrate how the integration of IP, technology and product teardowns can facilitate the setting of a strategic product development direction, one of the 17 technology categories will serve as an example. By far the most common form of blood glucose monitoring is self-monitoring blood glucose (SMBG). Currently, SMBG accounts for 97% of the diabetes monitoring market, as these products are widely reimbursed and approved, as well as relatively cheap and simple to use. These are the traditional finger-stick and blood test instruments.

 
 Figure 4: Abbott FreeStyle blood glucose meter.

Although a well-established market, growth in this area is being driven by strong demand in emerging markets, while new products that enhance ease-of-use, improve accuracy and facilitate data management and sharing are providing growth opportunities in the developed world. An analysis of this technology category reveals that many of the leading IP assignees also are among the leading product providers. Figure 2 displays the top 20 assignees in this category. While a number of them are also leading sellers of products in the category, it is interesting, as well, to see the other companies in this area. In addition, further analysis of the target area from a time perspective as shown in Figure 3 often can reveal not only where a company (or technology) has been but where it may be going.

As mentioned previously, a solid technology evaluation programme includes the analysis of a physical product. In the diabetes product space, UBM TechInsights has analysed products

 
 Figure 5: Inside the FreeStyle BGM.

ranging from blood glucose meters to insulin pumps and smartphone accessories. By integrating the market information, technology and IP with the product itself, a thorough picture of where things may be going begins to appear. Figures 4 and 5 provide a “look under the hood” of a popular BGM, the Abbott FreeStyle. However, the impact of the consumer upon the evolution of medical design can be seen in Figure 6, which shows the AgaMatrix iBGStar, a BGM designed to interface directly with an iPhone.

So what has this analysis indicated about the state of diabetes medical device technology today? Consumer demand for reduced levels of discomfort indicates a strong pull for noninvasive monitoring technology with a great deal of patent activity in this area. However, the commercialisation of minimally invasive or noninvasive products remains

a challenge. There are a number of active smaller companies in these emerging areas with potential for significant market disruption. We expect the large companies to be watching this space closely. While medical device advances will certainly continue and developments in monitoring technology of the chronically ill will make diabetes treatment more manageable, the promise of more comfortable and effective treatments through medical device technology continues to be a goal on the horizon.

Figure 6: AgaMatrix iBGStar blood glucose monitor.

The pace of fundamental development in the areas of monitoring and treatment of diabetes appears to have slowed while the overall market continues to grow as the prevalence of the disease increases. The emphasis today tends to be on patient compliance, driven primarily by ease of use, and consumer product influences, which is leading to devices that emphasise look and feel as opposed to performance. Finally, the ultimate medical device solution—the artificial pancreas—continues to be a much sought technology limited by technical, biological and regulatory issues that prevent it from being viable in the foreseeable future. In the interim, emphasis on disease management via improved monitoring and compliance will continue to dominate the device side while the search for biological solutions continues.

 

 

William Betten
is Medical Technology Director at UBM TechInsights,
3000 Solandt Road
Ottawa, ON K2K 2X2, Canada
e-mail: bbetten@ubmtechinsights.com
www.ubmtechinsights.com



Find more content on:
Your rating: None Average: 2.5 (6 votes)


Login to post comments

Comment viewing options

Select your preferred way to display the comments and click "Save settings" to activate your changes.

I surprised with the analysis

I surprised with the analysis you made to make this particular publish incredible. Wonderful activity!
http://www.tpprocessing.com/

Good post. I learn some thing

Good post. I learn some thing tougher on distinct blogs everyday. Most commonly it really is stimulating to learn to read content material from other writers and exercise a specific thing there.http://vavavoomdanceandfitness.com/health-news/what-natural-herbs-are-good-for-erectile-dysfunction/

http://watermelonsprinkles.com

Cara daftar judi bola online lewat hp bisa dilakukan dengan mengisi formulir terlebih dahulu pada website yang sudah disediakan yang diakses http://watermelonsprinkles.com

Well, this got me thinking

Well, this got me thinking what other workouts are good for those of us who find ourselves on the road or have limited equipment options.What Men Secretly Want

Generally I don’t read

Generally I don’t read article on blogs, but I would like to say that this write-up very forced me to check out and do so! Your writing style has been amazed me. Thanks, quite nice article. online web resources

a noted medical market

a noted medical market research firm, recently completed an analysis that included not just a market overview, but also a deep dive into the technology and intellectual local SEO service

I hope this discussion brings

I hope this discussion brings a new life for Somalia. Government and military must be working together. Foreclosure attorneys

Excellent Blog! I would like

Excellent Blog! I would like to thank for the efforts you have made in writing this post. I am hoping the same best work from you in the future as well. I wanted to thank you for this websites! Thanks for sharing. Great websites! business energy

I like viewing web sites

I like viewing web sites which comprehend the price of delivering the excellent useful resource free of charge. I truly adored reading your posting. Thank you! Lovetraction Line

the current diabetes device

the current diabetes device market, they continue to have large gaps in their patent and product portfolios link wheel building

Should there be another

Should there be another persuasive post please do share it the next time, I’ll be surely waiting for it.
cross country home warranty

home warranty

Awesome and interesting article. Great things you've always shared with us
bge home warranty
total protect home warranty reviews

You have a real ability for

You have a real ability for writing unique content. I like how you think and the way you represent your views in this article. I agree with your way of thinking. Thank you for sharing. Daftar Taruhan Bola Bank Mandiri

recently completed an

recently completed an analysis that included not just a market overview, but also a deep dive into the technology and intellectual property local SEO package

however it was another joy to

however it was another joy to see It is such an important topic and ignored by so many, even professionals. professionals. I thank you to help making people more aware of possible issues. Riley

I really like the dear

I really like the dear information you offer in your articles. I’m able to bookmark your site and show the kids check out up here generally. Im fairly positive theyre likely to be informed a great deal of new stuff here than anyone else!
https://www.uk-courtesans.com/

I am extremely enjoying

I am extremely enjoying reading your well written articles. it's such as you pay plenty of effort and time on your journal. I actually have bookmarked it and that i am wanting forward to reading new articles. volverconella.org

I would likewise persuade

I would likewise persuade pretty much every individual to spare this site page for any most loved help to support posted the appearance.... خرید وی پی ان

Lots of thanks for this

Lots of thanks for this post.I think it is a very good post. It helps us many away. So many many thanks for this article. driver updater pro tweak registration key

I am always searching online

I am always searching online for articles that can help me. There is obviously a lot to know about this. I think you made some good points in Features also. Keep working, great job ! www.menangcasino.com

An interesting dialogue is

An interesting dialogue is price comment. I feel that it is best to write more on this matter, it may not be a taboo topic however usually individuals are not enough to talk on such topics. To the next. Cheers. local SEO packages

very spectacular possibility

very spectacular possibility to read critical reviews from this site Super Bowl 2016

t

I have enjoyed this great information so much. This was really very interesting and helpful to read. I cant wait to read more from this site.
Dance Mat Typing

top websites

GATE score is considered in various Government undertaking and private companies to recruit technical staff and engineers. gate exam, gate 2016 GATE 2016 notification

I have never expected

I have never expected something less than this from you and you have not disappointed me at all. How To Cure Gastritis Naturally

Through this post, I know

Through this post, I know that your good knowledge in playing with all the pieces was very helpful. I notify that this is the first place where I find issues I've been searching for. You have a clever yet attractive way of writing.Love Traction Lines Review

the number of grants and

the number of grants and applications has doubled during the last six years.
Although a few large companies have a substantial share of the current diabetes device market, totally free stuff

Mmm.. good to be here in your

Mmm.. good to be here in your article or post, whatever, I think I should also work hard for my own website like I see some good and updated working in your site. xarelto lawsuit lawyers

I recently found many useful

I recently found many useful information in your website especially this blog page. Among the lots of comments on your articles. Thanks for sharing. Auto accident attorney

Wow, cool post. I’d like to

Wow, cool post. I’d like to write like this too – taking time and real hard work to make a great article… but I put things off too much and never seem to get started. Thanks though.
Health And Fitness Measurement

Regular visits listed here

Regular visits listed here are the easiest method to appreciate your energy, which is why why I am going to the website everyday, searching for new, interesting info. Many, thank you!Love Traction Lines PDF

t

I have enjoyed this great information so much. This was really very interesting and helpful to read. I cant wait to read more from this site.
Dance Matt Typing

Thank you a lot for providing

Thank you a lot for providing individuals with a very spectacular possibility to read critical reviews from this site. how to potty train easily

You make so many great points

You make so many great points here that I read your article a couple of times.
pregnancy miracle book lisa olson

No matter how you spend the

No matter how you spend the next 18 months you’re never going to grow another four inches, so whether you work out with personal coaches or strap it on in the SEC, the same critical questions will hang over your 5-11 head come draft day. mumbai matka

I was reading your article

I was reading your article and wondered if you had considered creating an ebook on this subject. Your writing would sell it fast. You have a lot of writing talent. HamiltonRealEstate

Sistemi & Consulenze Servizi

Sistemi & Consulenze Servizi per la Qualità Aziendale Progettazione, Implementazione e Mantenimento sistemi di Gestione, certificazioni,iso 9001, iso 14001,iso 22000,brc ifs,ohsas 18001,iso 22005,en1090,iso 27001,Halal,Kosher, consulenza e formazione nelle aree salute e sicurezza sul lavoro, igiene e sicurezza alimentare ,prevenzione incendi, gestione ambiente, privacy.Operiamo su tutto il territorio nazionale il nostro CORE è nelle regione Toscana Umbria e Lazio. fs gas Livorno

I feel strongly about it and

I feel strongly about it and love learning more on this topic. If possible, as you gain expertise, הסעות מלוטון ללונדון

I admit, I have not been on

I admit, I have not been on this web page in a long time... however it was another joy to see It is such an important topic and ignored by so many, even professionals. professionals. I thank you to help making people more aware of possible issues.

http://www.sgxcat.com/

Great Article it its really

Great Article it its really informative and innovative keep us posted with new updates. its was really valuable. thanks a lot. فیلتر شکن cisco

I am happy to find your

I am happy to find your distinguished way of writing the post.
Cellulite factor system

Thanks for taking the time to

Thanks for taking the time to discuss this, I feel strongly about it and love learning more on this topic. steroid sources

This amazing site will be

This amazing site will be interesting and as well as heaped with important material. Have expressing and that I will forever assist this site
iklan baris

Hmm… I read blogs on a

Hmm… I read blogs on a similar topic, but i never visited your blog. I added it to favorites and i’ll be your constant reader. HamiltonRealEstate

Thanks for sharing this

Thanks for sharing this interesting blog with us.My pleasure to being here on your blog..I wanna come back here for new post from your site. new smyrna beach fishing charters

Our mission is to provide

Our mission is to provide clients the highest quality tattoo that the industry offers. We specializes in realistic, 3D, portrait, water color, and japanese tattoos. Our studio provides a professional and clean work environment that utilizes the latest state of the art sterilization procedures. We customize each design so your personal preferences can make your tattoo unique and very personal to you. The studio is fully licensed and located just a few blocks south of the Mall of America in Bloomington, Minnesota near the Minneapolis-St Paul International Airport. We are in the same building as the Eagles Club. While most of our works are done by appointment we also offer walk-ins based upon our availability. However, we suggest you call in to check availability prior to your visit. Tattoo shop in st. paul

Great Information sharing ..

Great Information sharing .. I am very happy to read this article .. thanks for giving us go through info.Fantastic nice. I appreciate this post.
services entretien ménager montréal

Two big thumbs up for this

Two big thumbs up for this top notch blog post. I really liked reading this. I learned a lot of new stuff reading this. I just hope that you can keep this up in the future as well. how to get your ex back

Shirt Agency offers custom

Shirt Agency offers custom screen printing and embroidery on t-shirts, jackets, sweatshirts and accessories.Shirt Agency works to make any format of artwork looks its absolute best. Whether your artwork is still a hand drawn concept or a finished vector we have a team of people ready to help you make your print look perfect. Feel free to call us to discuss your design needs. shirt maker

Such a beautifully composed

Such a beautifully composed article this is. It's a shame not a lot of people can see this. Still, you must go on with this venture of yours and keep surprising us! sewing machines for beginners